Atsetonemichesky syndrome at children – the dangerous simptomokompleksny process caused by a metabolic disorder and accumulation in blood of ketone bodies. Its timely diagnostics and treatment reduces risk of development of adverse effects.
What is an atsetonemichesky syndrome
As a rule, this pathological state meets at children with neuroartricheskim diathesis - genetically caused violation of exchange of uric acid and the purinovy bases. It contributes to the development of serious violations of functions of internals of the child.
The Atsetonemichesky syndrome is shown by crises: an acetone smell from a mouth, intoxication, repeated vomiting with an acetone smell, diarrhea or a delay of a chair, spastic belly-aches, dehydration, subfebrilny body temperature. At a heavy current, meningealny symptoms and spasms usually appear. Attacks of an atsetonemichesky syndrome begin to appear at the age of 2-3 years and disappear by 12-13 years.
Reasons of development of pathology
In most cases the atsetonemichesky syndrome is caused by absolute or relative insufficiency of carbohydrates in the child's diet and also prevalence in it fatty acids and ketogene amino acids. Insufficiency of enzymes of a liver and violation of process of removal of ketone bodies contributes to the development of pathology. The imbalance of a metabolism has toxic effect on nervous system and digestive tract. Various infections, intoxications, stresses, violations of food and severe pain can become provocative factors of an atsetonemichesky syndrome. Development of this pathology in newborns is caused by a nephropathy (late toxicosis) of mother during pregnancy.
Treatment of an atsetonemichesky syndrome
At atsetonemichesky crises the stay of the child in a hospital is shown. To it the dietary correction including intake of the easily acquired carbohydrates, restriction of fats and plentiful fractional drink of alkaline mineral water and the combined solutions is carried out (Regidron, Tsitorglyukosolan). Besides, the cleaning enemas with soda solution neutralizing ketone bodies in intestines are appointed. At severe dehydration the intravenous drop administration of salt solutions and glucose is carried out. Symptomatic therapy provides use of antiemetic medicines, spasmolysants and sedatives. At adequate treatment the symptoms of crisis disappear in 2-5 days. During the mezhpristupny periods the child is observed by the pediatrician. Dairy and vegetable food, hardening, prevention of infectious diseases and psychoemotional loadings is recommended to him. Besides, preventive courses of gepatoprotektor, enzymes, sedative medicines and polyvitamins are appointed.