The disease of Kawasaki affects children of all races and nationalities, but most often occurs in Japanese. Can seriously complicate work of heart and vessels and to lead to a myocardial infarction.
Disease of Kawasaki – the rare disease for the first time described in Japan. Strikes children 8 years, most often are younger than boys. The Japanese children are much more subject to this illness, than children of other nationalities and races. The disease of Kawasaki causes sharp system nekrotiziruyushchiya vaskulit. At the same time large, average and small arteries are surprised.
Reasons and symptoms
Causes of illness are up to the end unknown. The seasonal variability and recurrence of a disease allows to assume its infectious nature, that is why it is connected with influence of a retrovirus as the illness arises suddenly and strikes children with the weakened immunity. The disease begins sharply, causing temperature increase of a body, hyperaemia of conjunctivas, dryness of lips and a mucous membrane of an oral cavity. Further the body of the kid becomes covered by polymorphic or skarlatinopodobny rashes, brushes and feet swell. The child from 12 to 36 days are in a fever. On the second week of a disease the rash and conjunctivitis disappear, lymph nodes return to the normal state, and language gains crimson color, fingers of hands and legs are exposed to lamellar peeling.
The danger of this disease is that it gives a serious complication on heart. The doctor can diagnose arthralgia, a priglushennost of warm tones, a kardiomegaliya, systolic noise and also increase in the sizes of a liver. Involvement of heart in pathological process can happen in the first days of a disease or, on the contrary, after crisis. At a sharp form of a disease in a myocardium (cardiac muscle) the inflammation develops. Such process most often proceeds without consequences, but there can sometimes be stagnant heart failure. The weakened cardiac muscle cannot effectively perform the work, causing accumulation of liquid in fabrics and hypostases. In one case from five heavy complications from heart and vessels develop. Walls of the last lose the elasticity and elasticity, forming pockets – aneurysms. It leads to formation of blood clots, and, as a result, a myocardial infarction.
Treatment, first of all, is directed to protection of a cardiovascular system. At a disease of Kawasaki invariable medicine remains aspirin which not only reduces high temperature, but also dilutes blood, interfering with formation of clots and renders powerful anti-inflammatory effect. At injury of coronary arteries, "Acetilsalicylic acid" is appointed small doses for an appreciable length of time. And though aspirin is not recommended for application for children up to 12 years, at a disease of Kawasaki such therapy is justified. Besides, daily intravenous injections of immunoglobulin within 5–7 days are shown. This medicine promotes increase in passive immunity of the patient and his recovery. The last researches in the field of treatment of this disease proved efficiency of use of "Heparin" and regular trainings by physical education.